Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 10/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 2/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971445 | 0.81 | RORC (0.48) | RORCHTR6BRD4FBP1 | |
| SCHEMBL16618633 | 0.81 | RORC (0.47) | RORCHTR6HDAC1HDAC2HDAC6 | |
| SCHEMBL19971362 | 0.81 | RORC (0.48) | RORCBRD4 | |
| SCHEMBL16626634 | 0.78 | RORC (0.45) | RORCHTR6HDAC1HDAC2HDAC6 | |
| SCHEMBL19971353 | 0.74 | HTR6 (0.41) | RORCHTR6HDAC1HDAC2HDAC6 | |
| SCHEMBL19971366 | 0.73 | HTR6 (0.41) | HTR6BRD4 | |
| SCHEMBL19971533 | 0.72 | HTR6 (0.39) | RORCHTR6MEN1KMT2AL3MBTL1 | |
| SCHEMBL19971346 | 0.72 | IDE (0.41) | HTR6HDAC1MEN1KMT2A | |
| SCHEMBL2415052 | 0.71 | MEP1B (0.43) | HTR6HDAC1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19971354 | 0.71 | HTR6 (0.38) | HTR6ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |