Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626434 | 0.92 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DCSNK2A1 | |
| Hydrochloric Acid SCHEMBL16619061 | 0.92 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DCSNK2A1 | |
| SCHEMBL16626428 | 0.89 | HTR6 (0.41) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL16618670 | 0.89 | NAMPT (0.41) | PDE4APDE4BPDE4CPDE4DIDE | |
| Hydrochloric Acid SCHEMBL16619520 | 0.89 | HTR6 (0.40) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL16626675 | 0.88 | HTT (0.38) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL16626418 | 0.88 | NAMPT (0.41) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL16626702 | 0.88 | BCL6 (0.40) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL16626444 | 0.88 | IDE (0.38) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL17971517 | 0.88 | IDE (0.39) | PDE4APDE4BPDE4CPDE4DIDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |