Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | IDE | P14735 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.34 |
| ▸ | TNFSF11 | O14788 | 4/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618605 | 0.84 | PRMT5 (0.36) | HTR6IDEPTGER2TNFSF11HDAC1 | |
| SCHEMBL19971344 | 0.82 | IDE (0.40) | HTR6IDEPDE4APDE4BPDE4C | |
| SCHEMBL1156756 | 0.73 | PTGER2 (0.38) | PTGER2HDAC1 | |
| Carbamic Acid SCHEMBL4791646 | 0.72 | PTGER2 (0.39) | PTGER2HDAC1 | |
| SCHEMBL16619076 | 0.72 | HTR6 (0.47) | HTR6IDETNFSF11HDAC1HDAC2 | |
| SCHEMBL16619044 | 0.71 | HTR6 (0.45) | HTR6IDETNFSF11HDAC1HDAC2 | |
| SCHEMBL2411045 | 0.71 | PTGER2 (0.33) | HTR6IDEPTGER2 | |
| SCHEMBL16619302 | 0.70 | HTR6 (0.44) | HTR6IDEPTGER2TNFSF11HDAC1 | |
| SCHEMBL16619409 | 0.70 | HTR6 (0.44) | HTR6IDEPTGER2TNFSF11HDAC1 | |
| SCHEMBL1156603 | 0.69 | PTGER2 (0.36) | PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |