Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 5/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971385 | 0.82 | HTR6 (0.36) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16618605 | 0.80 | PRMT5 (0.36) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28068083 | 0.75 | IDE (0.43) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19971473 | 0.74 | PDE4A (0.44) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28068056 | 0.73 | IDE (0.42) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19984047 | 0.73 | HTR6 (0.43) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28068051 | 0.73 | IDE (0.41) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16619172 | 0.71 | HTR6 (0.46) | IDEHTR6 | |
| SCHEMBL16619000 | 0.71 | HTR6 (0.46) | IDEHTR6 | |
| SCHEMBL16618718 | 0.71 | PDE4A (0.43) | IDEPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |