SCHEMBL24522014

SCHEMBL24522014

Cc1cc(C)c(S)c(S)c1C

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1610330 0.87 CYP3A4 (0.33) CYP3A4TSHRMAPK1
SCHEMBL1610039 0.81 CYP3A4 (0.30) CYP3A4TSHRMAPK1
SCHEMBL28612614 0.80 CYP3A4 (0.33) CYP3A4TSHRMAPK1
SCHEMBL19972015 0.75 CYP3A4 (0.38) CYP3A4TSHRMAPK1
SCHEMBL18473240 0.75 CA1 (0.43) CYP3A4TSHR
SCHEMBL24521974 0.75 ALDH1A1 (0.38)
SCHEMBL19972039 0.75 CYP3A4 (0.43) CYP3A4TSHRMAPK1
SCHEMBL5355969 0.71 POLB (0.30)
SCHEMBL22132566 0.71 PGK1 (0.34)
SCHEMBL5357171 0.71 POLB (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015511-A1 OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS CARNEGIE MELLON UNIVERSITY (US) 2022-06-22 EP disclosed