SCHEMBL19972877

SCHEMBL19972877

Cc1c(C)c(C)c(C(C)C)c(O)c1C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.33
BCL2L1 Q07817 1/20 0.33
MCL1 Q07820 1/20 0.33
BCL2L2 Q92843 1/20 0.33
LDHA P00338 1/20 0.32
LDHB P07195 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
FAAH O00519 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
GABRA1 P14867 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19183569 0.92 BCL2 (0.32) BCL2BCL2L1MCL1BCL2L2LDHA
SCHEMBL9070220 0.91 BCL2 (0.34) BCL2BCL2L1MCL1BCL2L2LDHA
SCHEMBL14201680 0.86 LDHA (0.35) BCL2BCL2L1MCL1BCL2L2LDHA
SCHEMBL1242989 0.83 BCL2 (0.35) BCL2BCL2L1MCL1BCL2L2LDHA
SCHEMBL19020514 0.82 LDHA (0.36) BCL2BCL2L1MCL1BCL2L2LDHA
SCHEMBL23943247 0.80 LDHA (0.35) BCL2BCL2L1MCL1BCL2L2LDHA
SCHEMBL23848679 0.79
SCHEMBL23867809 0.79 GABRA1 (0.33) BCL2BCL2L1MCL1BCL2L2LDHA
SCHEMBL4967470 0.79 BCL2 (0.34) BCL2BCL2L1MCL1BCL2L2LDHA
SCHEMBL8330118 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018053344-A1 SWEETNESS ENHANCING VOLATILE COMPOSITIONS AND METHODS OF INCREASING PERCEIVED SWEETNESS OF A COMESTIBLE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2018-03-22 WO claimed
US-11744273-B2 Sweetness enhancing volatile compositions and methods of increasing perceived sweetness of a comestible UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-09-05 US disclosed
US-20190254322-A1 SWEETNESS ENHANCING VOLATILE COMPOSITIONS AND METHODS OF INCREASING PERCEIVED SWEETNESS OF A COMESTIBLE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2019-08-22 US disclosed
WO-2018053344-A1 SWEETNESS ENHANCING VOLATILE COMPOSITIONS AND METHODS OF INCREASING PERCEIVED SWEETNESS OF A COMESTIBLE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2018-03-22 WO disclosed