SCHEMBL19973215

SCHEMBL19973215

C[SiH](C)O[Si](C)(C)NCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
IDO1 P14902 2/20 0.40
THRB P10828 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HTT P42858 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
TP53 P04637 1/20 0.37
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36
ADH1A P07327 1/20 0.36
ADH7 P40394 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
CA12 O43570 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19973296 0.88 MAPT (0.37) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL15135122 0.78 CYP3A4 (0.45) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL26964162 0.78 CYP3A4 (0.45) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL3273386 0.76 IDO1 (0.54) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL15949871 0.73 ALDH1A1 (0.41) IDO1TP53ALDH1A1HPGD
SCHEMBL6907584 0.72 IDO1 (0.50) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL16096372 0.71 MAPT (0.46) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL11099246 0.71 CYP3A4 (0.46) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL28924922 0.71 CYP3A4 (0.46) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL3122253 0.71 IDO1 (0.52) CYP3A4MAPTKDM4EIDO1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3516089-B1 COMPOSITIONS AND METHODS FOR THE DEPOSITION OF SILICON OXIDE FILMS VERSUM MAT US LLC (US) 2023-12-20 EP claimed
EP-3516089-A1 COMPOSITIONS AND METHODS FOR THE DEPOSITION OF SILICON OXIDE FILMS Versum Materials US, LLC (US) 2019-07-31 EP claimed
WO-2018053129-A1 COMPOSITIONS AND METHODS FOR THE DEPOSITION OF SILICON OXIDE FILMS VERSUM MATERIALS US, LLC (US) 2018-03-22 WO claimed