SCHEMBL28924922

SCHEMBL28924922

CO[Si](NCc1ccccc1)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
IDO1 P14902 2/20 0.43
THRB P10828 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HTT P42858 3/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH7 P40394 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopropane SCHEMBL1138573 0.94 CYP3A4 (0.42) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL25408736 0.83 MEN1 (0.61) MAPTMEN1KMT2ATDP1SIGMAR1
SCHEMBL305780 0.81 ADH1B (0.37) CYP3A4MAPTKDM4EHTTADH1B
SCHEMBL7165865 0.81 CHRM2 (0.42) MAPTKDM4EIDO1THRBMEN1
SCHEMBL15135122 0.81 CYP3A4 (0.45) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL3273386 0.75 IDO1 (0.54) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL3122253 0.74 IDO1 (0.52) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL27929636 0.74 DRD4 (0.39) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL28806607 0.74 MEN1 (0.39) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL26964162 0.72 CYP3A4 (0.45) CYP3A4MAPTKDM4EIDO1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113508121-A VOC-free, aqueous and storage-stable N-vinylbenzylaminoalkyl-functional siloxanols and process for their preparation 赢创运营有限公司 2021-10-15 CN disclosed