Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 4/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974343 | 0.84 | PTGDR2 (0.45) | RBP4PTGDR2MRGPRX4 | |
| SCHEMBL19992928 | 0.83 | STS (0.47) | TRPV1ENPP2POLB | |
| SCHEMBL27486622 | 0.83 | CHRNB2 (0.44) | PTGDR2IDO1MRGPRX4POLB | |
| SCHEMBL1094396 | 0.83 | RBP4 (0.47) | RBP4PTGDR2SLC9A1TRPV1IDO1 | |
| SCHEMBL15012563 | 0.82 | RBP4 (0.46) | RBP4PTGDR2SLC9A1TRPV1IDO1 | |
| SCHEMBL21722815 | 0.81 | PTGDR2 (0.42) | RBP4PTGDR2TRPV1MRGPRX4 | |
| SCHEMBL6807066 | 0.81 | PTGDR2 (0.49) | PTGDR2MRGPRX4HTR2A | |
| SCHEMBL23858293 | 0.80 | TRPV1 (0.55) | RBP4PTGDR2SLC9A1TRPV1IDO1 | |
| SCHEMBL21722950 | 0.80 | PTGDR2 (0.48) | RBP4PTGDR2TRPV1MRGPRX4POLB | |
| SCHEMBL1094926 | 0.79 | PTGDR2 (0.55) | RBP4PTGDR2SLC9A1TRPV1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515897-A1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018053447-A1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |