Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486622 | 0.93 | CHRNB2 (0.44) | PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL19974321 | 0.86 | HTR2C (0.51) | CHRNB2CHRNA4CHRNB4CHRNA3PNMT | |
| SCHEMBL19974334 | 0.81 | RBP4 (0.45) | PTGDR2HTR2AMRGPRX4 | |
| SCHEMBL20303392 | 0.80 | CHRNB2 (0.44) | PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Trifluoroacetic Acid SCHEMBL21271258 | 0.80 | HTR2C (0.44) | PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28897105 | 0.78 | CA1 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3PNMT | |
| SCHEMBL19974343 | 0.78 | PTGDR2 (0.45) | PTGDR2KMT2AMRGPRX4 | |
| SCHEMBL27848652 | 0.76 | PTGDR2 (0.43) | PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL20503456 | 0.76 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3PNMT | |
| SCHEMBL29170876 | 0.75 | KMT2A (0.40) | PNMTNOS3NOS1NOS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |