SCHEMBL19974723

SCHEMBL19974723

O=C(O)NCCCCCCNC(=O)C(=O)C1CCC(=O)N1Cc1ccc(Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
KMT2A Q03164 2/20 0.49
P2RX7 Q99572 2/20 0.48
GAA P10253 1/20 0.48
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
USP2 O75604 1/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C19 P33261 2/20 0.45
CYP2C9 P11712 1/20 0.45
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
GFER P55789 2/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19975344 0.93 ALDH1A1 (0.49) ALDH1A1KMT2AP2RX7GAAALOX15
SCHEMBL19975067 0.91 P2RX7 (0.49) ALDH1A1KMT2AP2RX7GAAALOX15
SCHEMBL19975520 0.91 P2RX7 (0.49) ALDH1A1KMT2AP2RX7GAAALOX15
SCHEMBL19975060 0.91 P2RX7 (0.49) ALDH1A1KMT2AP2RX7GAAALOX15
SCHEMBL21176336 0.90 ALDH1A1 (0.51) ALDH1A1KMT2AP2RX7GAAALOX15
Hydrochloric Acid SCHEMBL19975083 0.89 ALDH1A1 (0.50) ALDH1A1KMT2AP2RX7GAAALOX15
SCHEMBL19974962 0.89 ALDH1A1 (0.50) ALDH1A1KMT2AP2RX7GAAUSP2
SCHEMBL21176270 0.89 ALDH1A1 (0.53) ALDH1A1KMT2AP2RX7GAAALOX15
SCHEMBL21176164 0.86 ALDH1A1 (0.55) ALDH1A1KMT2AP2RX7GAAALOX15
SCHEMBL21176333 0.86 DRD2 (0.48) ALDH1A1KMT2AP2RX7GAAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512836-A1 ANTIVIRAL COMPOUNDS Haplogen GmbH (AT) 2019-07-24 EP disclosed
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed