SCHEMBL19974846

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19974713	0.89	KMT2A (0.59)	KMT2AHTTHPGDMEN1ALDH1A1
	SCHEMBL21176211	0.88	KMT2A (0.53)	KMT2ANPC1MEN1MMP1MMP2
	SCHEMBL19975409	0.88	GBA1 (0.51)	KMT2AHTTHPGDMEN1ALDH1A1
	SCHEMBL21176241	0.82	KMT2A (0.46)	KMT2AHTTHPGDMEN1GAA
	SCHEMBL19974908	0.80	KMT2A (0.52)	KMT2ANPC1HTTHPGDGFER
	SCHEMBL19975513	0.78	CTSL (0.50)	KMT2ANPC1HPGDALDH1A1
	SCHEMBL19975391	0.77	ITGAV (0.45)	KMT2AHTTGAAALDH1A1SLC1A3
	SCHEMBL19974751	0.77	ITGAV (0.47)	KMT2AHPGDMEN1GAAALDH1A1
	SCHEMBL19975110	0.76	KMT2A (0.46)	KMT2AMEN1ALDH1A1SLC1A3SLC1A2
	SCHEMBL27407683	0.73	CA2 (0.49)	KMT2AHPGDMEN1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.