SCHEMBL19974907

SCHEMBL19974907

CC(C(O)C(=O)NCc1cccc(Cl)c1)N(C=O)C1CCOCC1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.43
MASP2 O00187 1/20 0.42
RXFP1 Q9HBX9 1/20 0.41
ADAM17 P78536 3/20 0.41
ALDH1A1 P00352 2/20 0.40
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAPK1 P28482 3/20 0.40
P2RX7 Q99572 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19975335 0.90 ALDH1A1 (0.48) KMT2AMASP2RXFP1ADAM17ALDH1A1
SCHEMBL19975248 0.85 ALDH1A1 (0.41) KMT2AMASP2RXFP1ADAM17ALDH1A1
SCHEMBL21183521 0.83 MAPK1 (0.42) KMT2AMASP2RXFP1ALDH1A1GAA
SCHEMBL19975126 0.80 ALDH1A1 (0.47) KMT2AMASP2RXFP1ADAM17ALDH1A1
SCHEMBL19974899 0.80 MAPK1 (0.47) KMT2AMASP2RXFP1ADAM17ALDH1A1
SCHEMBL19974811 0.79 MASP2 (0.47) KMT2AMASP2RXFP1ADAM17ALDH1A1
SCHEMBL19975435 0.78 MASP2 (0.46) KMT2AMASP2RXFP1ADAM17ALDH1A1
SCHEMBL19975379 0.77 ALDH1A1 (0.51) KMT2AMASP2RXFP1ADAM17ALDH1A1
SCHEMBL19975405 0.77 MASP2 (0.49) KMT2AMASP2RXFP1ADAM17ALDH1A1
SCHEMBL19975564 0.76 MASP2 (0.48) KMT2AMASP2RXFP1ADAM17ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356148-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2022-11-10 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
EP-3512836-A1 ANTIVIRAL COMPOUNDS Haplogen GmbH (AT) 2019-07-24 EP disclosed
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225575-A1 ANTIVIRAL COMPOUNDS PLA2G1B, PLA2G12A, PLA2G4C KMT2A 4031/4885MASP2 1122/4885RXFP1 1779/4885
US-20220356148-A1 ANTIVIRAL COMPOUNDS PLA2G12A, PLA2G1B, PLA2G4C KMT2A 4177/4885MASP2 862/4885RXFP1 2251/4885
US-11091428-B2 Antiviral compounds PLA2G1B, PLA2G12A, PLA2G4C KMT2A 4031/4885MASP2 1122/4885RXFP1 1779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.