SCHEMBL19974955

SCHEMBL19974955

CC(C(O)C(=O)NCC1CC1)N(C=O)CC1CCN(C(=O)O)CC1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
EPHX2 P34913 1/20 0.33
KMT2A Q03164 1/20 0.32
BRD4 O60885 1/20 0.32
SCN5A Q14524 1/20 0.31
SCN9A Q15858 1/20 0.31
KDM4E B2RXH2 1/20 0.31
PKM P14618 1/20 0.31
POLB P06746 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19975112 0.95 MEN1 (0.36) EPHX1KMT2AKDM4EPOLBALDH1A1
SCHEMBL21176196 0.85 KDM4E (0.47) EPHX1KMT2AKDM4EPKMPOLB
SCHEMBL19974838 0.84 SMN1; SMN2 (0.40) EPHX1EPHX2KMT2AALDH1A1GAA
SCHEMBL19975400 0.84 SMN1; SMN2 (0.40) EPHX1EPHX2KMT2AALDH1A1GAA
SCHEMBL19974937 0.83 ALDH1A1 (0.34) EPHX1EPHX2KMT2AKDM4EPOLB
SCHEMBL19974893 0.81 BRD4 (0.33) EPHX1EPHX2BRD4KDM4EPKM
SCHEMBL21176200 0.81 KDM4E (0.45) EPHX1KMT2AKDM4EPKMALDH1A1
SCHEMBL28767035 0.79 EPHX2 (0.40) EPHX1EPHX2KMT2ABRD4SCN5A
SCHEMBL28767036 0.79 EPHX2 (0.40) EPHX1EPHX2KMT2ABRD4SCN5A
SCHEMBL21183507 0.78 CTSD (0.36) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
EP-3512836-A1 ANTIVIRAL COMPOUNDS Haplogen GmbH (AT) 2019-07-24 EP disclosed
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225575-A1 ANTIVIRAL COMPOUNDS PLA2G1B, PLA2G12A, PLA2G4C EPHX1 372/4885EPHX2 1455/4885KMT2A 4031/4885
US-11091428-B2 Antiviral compounds PLA2G1B, PLA2G12A, PLA2G4C EPHX1 372/4885EPHX2 1455/4885KMT2A 4031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.