Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997491 | 0.86 | GPR142 (0.40) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1990025 | 0.77 | CHRM4 (0.40) | MEN1KMT2AALDH1A1ATMGRIN2D | |
| SCHEMBL1989631 | 0.77 | GRIN2D (0.46) | MEN1KMT2AALDH1A1GRIN2DGRIN3B | |
| SCHEMBL4566910 | 0.77 | GRIN2D (0.39) | ALDH1A1ATMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1990022 | 0.72 | HSD17B10 (0.40) | MEN1KMT2AALDH1A1GRIN2DGRIN3B | |
| Fumaric Acid SCHEMBL1988836 | 0.70 | GSK3B (0.46) | MEN1KMT2AALDH1A1KDM4EHTT | |
| Maleic Acid SCHEMBL1988834 | 0.70 | GSK3B (0.46) | MEN1KMT2AALDH1A1KDM4EHTT | |
| Maleic Acid SCHEMBL1988832 | 0.70 | GSK3B (0.46) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL4566908 | 0.70 | GPR142 (0.40) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1990957 | 0.69 | GSK3B (0.52) | MEN1KMT2ANPC1RAB9APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263587-B2 | Benzoxazepine compounds, their preparation and use | PIRAMAL HEALTHCARE LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| EP-2077846-B1 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LTD (IN) | 2011-10-12 | — | — | EP | disclosed |
| US-20110152247-A1 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Enterprises Limited (IN) | 2011-06-23 | — | — | US | disclosed |
| EP-2077846-A2 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Life Sciences Limited (IN) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008053446-A2 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152247-A1 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | GPR119, INSR, SLC5A1 | MEN1 2065/4885KMT2A 2764/4885ALDH1A1 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.