Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975376 | 0.84 | L3MBTL1 (0.40) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL21176264 | 0.79 | HPGD (0.43) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL30062960 | 0.78 | POLB (0.49) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL19974770 | 0.78 | POLB (0.49) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL19974773 | 0.78 | POLB (0.49) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL19974842 | 0.76 | KMT2A (0.43) | KMT2AALDH1A1HPGDPOLBCYP1A2 | |
| SCHEMBL19975415 | 0.76 | HPGD (0.42) | TSHRL3MBTL1ALDH1A1HPGDNPC1 | |
| SCHEMBL19975543 | 0.73 | HPGD (0.49) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL19974978 | 0.72 | CTSD (0.44) | TSHRL3MBTL1ALDH1A1RAB9ACYP3A4 | |
| SCHEMBL19975312 | 0.71 | LMNA (0.35) | MEN1KMT2AHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512836-A1 | ANTIVIRAL COMPOUNDS | Haplogen GmbH (AT) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |