Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.34 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975478 | 1.00 | DPP4 (0.40) | DPP4DPP7S1PR1DCAF1S1PR3 | |
| SCHEMBL19981240 | 0.79 | LMNA (0.40) | S1PR1DCAF1S1PR3CTSA | |
| SCHEMBL19981159 | 0.77 | DPP4 (0.38) | DPP4DPP7S1PR1 | |
| SCHEMBL19981353 | 0.77 | MAPT (0.43) | S1PR1S1PR3 | |
| SCHEMBL18078016 | 0.77 | DPP4 (0.45) | DPP4DPP7S1PR1CTSA | |
| SCHEMBL19867093 | 0.77 | CD274 (0.58) | DPP4DPP7S1PR1CTSAGABRA5 | |
| SCHEMBL18077936 | 0.77 | CD274 (0.58) | DPP4DPP7S1PR1CTSAGABRA5 | |
| SCHEMBL24218473 | 0.73 | S1PR1 (0.35) | DPP4DPP7S1PR1DCAF1S1PR3 | |
| SCHEMBL19981133 | 0.73 | DPP4 (0.36) | DPP4DPP7S1PR1DCAF1S1PR3 | |
| SCHEMBL19981143 | 0.73 | DPP4 (0.34) | DPP4DPP7S1PR1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |