Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BLVRB | P30043 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | DCAF1 | Q9Y4B6 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981248 | 0.93 | CTSA (0.47) | LMNATSHRCTSAMAOABLVRB | |
| SCHEMBL24218494 | 0.88 | LMNA (0.45) | LMNATSHRCTSAMAOABLVRB | |
| SCHEMBL19981233 | 0.87 | LMNA (0.44) | LMNATSHRCTSAMAOABLVRB | |
| SCHEMBL19981269 | 0.83 | CTSA (0.45) | LMNATSHRCTSAROCK2ROCK1 | |
| SCHEMBL19975480 | 0.79 | DPP4 (0.40) | CTSADCAF1S1PR3S1PR1 | |
| SCHEMBL19975478 | 0.79 | DPP4 (0.40) | CTSADCAF1S1PR3S1PR1 | |
| SCHEMBL18077936 | 0.78 | CD274 (0.58) | CTSAS1PR1 | |
| SCHEMBL19867093 | 0.78 | CD274 (0.58) | CTSAS1PR1 | |
| SCHEMBL18078210 | 0.78 | VSIR (0.55) | LMNATSHRDCAF1S1PR3S1PR1 | |
| SCHEMBL18078016 | 0.77 | DPP4 (0.45) | CTSAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |