SCHEMBL1997597

SCHEMBL1997597

O=C(CO)NC(CS)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
MAPT P10636 1/20 0.59
THRB P10828 1/20 0.59
ALOX15 P16050 1/20 0.59
NFKB1 P19838 1/20 0.59
PTGS2 P35354 1/20 0.59
THPO P40225 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
ACE P12821 1/20 0.53
FOLH1 Q04609 1/20 0.50
FNTA P49354 2/20 0.44
FNTB P49356 2/20 0.44
CA2 P00918 4/20 0.40
CA1 P00915 3/20 0.40
PTGS1 P23219 2/20 0.39
GSTK1 Q9Y2Q3 1/20 0.39
MME P08473 3/20 0.38
TGFBR1 P36897 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL367571 1.00 KDM4E (0.59) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4990899 0.84 KDM4E (0.61) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL8861972 0.84 KDM4E (0.61) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL929428 0.84 KDM4E (0.61) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL24308826 0.82 KDM4E (0.59) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL22117302 0.82 KDM4E (0.59) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL22117303 0.82 KDM4E (0.59) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4812263 0.81 TGFBR1 (0.56) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL1995530 0.81 TGFBR1 (0.56) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL1995531 0.81 TGFBR1 (0.56) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0721347-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS Beiersdorf Aktiengesellschaft (DE) 1996-07-17 EP claimed
WO-1995005852-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS BEIERSDORF AG (DE) 1995-03-02 WO claimed
US-11992518-B2 Molecular vaccines for infectious disease AGILENT TECHNOLOGIES, INC. (US) 2024-05-28 US disclosed
CN-108064308-B Method for producing double-stranded protein in bacteria 豪夫迈·罗氏有限公司 2023-06-09 CN disclosed
US-10968269-B1 MHC multimers in borrelia diagnostics and disease AGILENT TECHNOLOGIES, INC. (US) 2021-04-06 US disclosed
US-20210047383-A1 MHC Multimers in Borrelia Diagnostics and Disease DAKO DENMARK APS (DK) 2021-02-18 US disclosed
US-20200347103-A1 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS AGILENT TECHNOLOGIES INC (US) 2020-11-05 US disclosed
US-10611818-B2 MHC multimers in tuberculosis diagnostics, vaccine and therapeutics AGILENT TECHNOLOGIES, INC. (US) 2020-04-07 US disclosed
US-20190314471-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE AGILENT TECHNOLOGIES, INC. 2019-10-17 US disclosed
US-10369204-B2 Molecular vaccines for infectious disease DAKO DENMARK A/S (DK) 2019-08-06 US disclosed
US-20120258126-A1 Molecular Vaccines for Infectious Disease DAKO DENMARK A/S (DK) 2012-10-11 US disclosed
WO-2009039854-A2 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS DAKO DENMARK A/S (DK) 2009-04-02 WO disclosed
EP-0797427-B1 AGENTS ACTING AGAINST HYPERREACTIVE AND HYPOACTIVE, DEFICIENT SKIN CONDITIONS AND MANIFEST DERMATITIDES BEIERSDORF AG (DE) 2003-05-14 EP disclosed
EP-1300138-A2 Agents effective against hyperreactive and hypoactive deficient skin conditions as well as manifest dermatitis Beiersdorf AG (DE) 2003-04-09 EP disclosed
US-6180662-B1 MIXTURE OF CINNAMIC ACID, ANTIOXIDANT, ENZYME, MICROBIOCIDES AND VIRICIDES BEIERSDORF AG (DE) 2001-01-30 US disclosed
US-5952373-A APPLYING TO THE SKIN AN EFFECTIVE AMOUNT OF ONE OR MORE FLAVONOIDS BEIERSDORF AG (DE) 1999-09-14 US disclosed
EP-0797427-A1 AGENTS ACTING AGAINST HYPERREACTIVE AND HYPOACTIVE, DEFICIENT SKIN CONDITIONS AND MANIFEST DERMATITIDES Beiersdorf Aktiengesellschaft (DE) 1997-10-01 EP disclosed
EP-0721347-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS Beiersdorf Aktiengesellschaft (DE) 1996-07-17 EP disclosed
WO-1996018381-A1 AGENTS ACTING AGAINST HYPERREACTIVE AND HYPOACTIVE, DEFICIENT SKIN CONDITIONS AND MANIFEST DERMATITIDES BEIERSDORF AG (DE) 1996-06-20 WO disclosed
WO-1995005852-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS BEIERSDORF AG (DE) 1995-03-02 WO disclosed