Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975996 | 0.75 | LIPG (0.46) | ENPP2 | |
| SCHEMBL16576658 | 0.75 | TAAR1 (0.37) | AKR1B1HPGDSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL4566260 | 0.74 | AKR1B1 (0.41) | AKR1B1SMN1; SMN2MAPK1KMT2AADRA2A | |
| SCHEMBL19975967 | 0.73 | LIPG (0.34) | — | |
| SCHEMBL24425186 | 0.71 | ENPP2 (0.36) | AKR1B1HPGDSMN1; SMN2LMNACYP2D6 | |
| SCHEMBL29352520 | 0.65 | TSHR (0.48) | KMT2AMEN1LMNACYP3A4CYP2D6 | |
| SCHEMBL4991 | 0.65 | TSHR (0.48) | KMT2AMEN1LMNACYP3A4CYP2D6 | |
| SCHEMBL31125058 | 0.65 | ENPP2 (0.39) | LMNAENPP2 | |
| SCHEMBL4129 | 0.65 | TSHR (0.47) | LMNAMAPTENPP2 | |
| SCHEMBL29404220 | 0.65 | TSHR (0.47) | LMNAMAPTENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920085-B2 | Boronic acid conjugates of oligonucleotide analogues | SAREPTA THERAPEUTICS, INC. (US) | 2018-03-20 | — | — | US | disclosed |