Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MLYCD | O95822 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ESRRG | P62508 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23222129 | 0.90 | HDAC3 (0.52) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL16964203 | 0.86 | MLYCD (0.54) | MLYCDTSHRALDH1A1BLMPMP22 | |
| SCHEMBL16964231 | 0.84 | MLYCD (0.55) | LMNAMLYCDALDH1A1MAPK1HDAC3 | |
| SCHEMBL507116 | 0.83 | HDAC3 (0.54) | MLYCDTSHRALDH1A1ESRRGBLM | |
| SCHEMBL9344489 | 0.83 | KDM4E (0.68) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL16964142 | 0.83 | MLYCD (0.54) | MLYCDHDAC3CYP1A2 | |
| SCHEMBL19938019 | 0.83 | MLYCD (0.67) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL16964303 | 0.83 | MLYCD (0.58) | LMNAMLYCDALDH1A1MAPK1HDAC3 | |
| SCHEMBL18359001 | 0.83 | LMNA (0.62) | LMNAMLYCDALDH1A1HDAC3POLB | |
| SCHEMBL8507100 | 0.82 | HDAC3 (0.62) | LMNAMLYCDESRRGHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | disclosed |