Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21297671 | 0.84 | S1PR2 (0.32) | ALDH1A1S1PR2S1PR1S1PR3TP53 | |
| SCHEMBL21297672 | 0.77 | LOXL2 (0.42) | ALDH1A1SMYD3HTTSMN1; SMN2KDM4E | |
| SCHEMBL16784862 | 0.76 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPTCNR2 | |
| SCHEMBL101427 | 0.75 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAPTTP53KDM4E | |
| SCHEMBL100588 | 0.73 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL6172313 | 0.73 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTSMYD3KDM5A | |
| SCHEMBL4863083 | 0.73 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTSMYD3KDM5A | |
| SCHEMBL206112 | 0.72 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAPTHCRTR1HCRTR2 | |
| SCHEMBL22259789 | 0.72 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPTHCRTR1HCRTR2 | |
| SCHEMBL16594468 | 0.71 | NR2F2 (0.43) | SMYD3HTTSMN1; SMN2KDM4ENR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | ALDH1A1 1447/4885L3MBTL1 3368/4885MAPT 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.