Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.42 |
| ▸ | PDE1A | P54750 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15500277 | 0.88 | FABP4 (0.40) | PDE5APDE1APDE1BPDE1CALDH1A1 | |
| SCHEMBL17299116 | 0.85 | PDE5A (0.38) | PDE5APDE1APDE1BPDE1CALDH1A1 | |
| SCHEMBL21297663 | 0.81 | MAPK8 (0.35) | ALDH1A1MAPK1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL15500255 | 0.78 | AKR1C3 (0.36) | MAPK1BCHEACHEPOLBHDAC6 | |
| SCHEMBL17689339 | 0.77 | LMNA (0.50) | PDE5AALDH1A1LMNAMAPK1AKR1B1 | |
| SCHEMBL101553 | 0.76 | EPHX1 (0.39) | MAPK1POLBKDM4E | |
| SCHEMBL19976541 | 0.76 | CNR2 (0.39) | S1PR1S1PR3S1PR2 | |
| SCHEMBL17689341 | 0.74 | LMNA (0.50) | ALDH1A1LMNAMAPK1AKR1B1CYP1A2 | |
| SCHEMBL21524634 | 0.74 | LMNA (0.47) | PDE5APDE1APDE1BPDE1CALDH1A1 | |
| SCHEMBL101551 | 0.69 | METTL3 (0.31) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |