Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21297662 | 0.86 | POLB (0.39) | POLBMAPK1SMN1; SMN2FABP4AKR1B1 | |
| SCHEMBL178267 | 0.80 | TLR7 (0.35) | MAPK1TLR7 | |
| SCHEMBL178132 | 0.77 | POLB (0.38) | POLBMAPK1SMN1; SMN2FABP4LMNA | |
| SCHEMBL19976533 | 0.75 | POLB (0.35) | POLBMAPK1SMN1; SMN2LMNATLR7 | |
| SCHEMBL21297676 | 0.74 | LMNA (0.36) | POLBMAPK1AKR1B1LMNAPDE5A | |
| SCHEMBL19976557 | 0.71 | POLB (0.37) | POLBMAPK1SMN1; SMN2FABP4LMNA | |
| SCHEMBL21524634 | 0.70 | LMNA (0.47) | POLBMAPK1SMN1; SMN2AKR1B1LMNA | |
| SCHEMBL178263 | 0.69 | LMNA (0.35) | POLBMAPK1AKR1B1LMNAPTGS1 | |
| SCHEMBL16252079 | 0.69 | TLR7 (0.34) | TLR7 | |
| SCHEMBL17689339 | 0.69 | LMNA (0.50) | POLBMAPK1SMN1; SMN2FABP4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |