Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178266 | 0.77 | MEN1 (0.32) | — | |
| SCHEMBL178270 | 0.73 | POLB (0.39) | POLBMAPK1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL19063140 | 0.72 | POLB (0.38) | POLBMAPK1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10127310 | 0.71 | L3MBTL1 (0.31) | — | |
| SCHEMBL10127672 | 0.71 | TLR7 (0.32) | — | |
| SCHEMBL19976534 | 0.71 | POLB (0.36) | POLBMAPK1SMN1; SMN2LMNAFABP4 | |
| SCHEMBL22259601 | 0.70 | POLB (0.36) | POLBMAPK1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10126841 | 0.70 | POLB (0.39) | POLBMAPK1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL21524634 | 0.65 | LMNA (0.47) | POLBMAPK1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10127256 | 0.64 | HPGD (0.40) | SMN1; SMN2HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |