Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 11/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976803 | 0.92 | MAPK1 (0.38) | MAPK1POLBALDH1A1HPGDNAMPT | |
| SCHEMBL19976807 | 0.91 | MAPK1 (0.37) | MAPK1POLBHPGDNAMPTDGAT2 | |
| SCHEMBL19976784 | 0.90 | MAPK1 (0.38) | MAPK1POLBNAMPTMAP2K4DGAT2 | |
| SCHEMBL19976786 | 0.86 | HPGD (0.48) | MAPK1ALDH1A1HPGDNAMPTDGAT2 | |
| SCHEMBL19976833 | 0.85 | HPGD (0.41) | MAPK1POLBALDH1A1HPGDMAP2K4 | |
| SCHEMBL16752823 | 0.84 | MAP2K4 (0.44) | MAPK1MAP2K4CDK2 | |
| SCHEMBL16752820 | 0.84 | MAP2K4 (0.44) | MAPK1MAP2K4CDK2 | |
| SCHEMBL16769269 | 0.84 | MAP2K4 (0.44) | MAPK1MAP2K4CDK2 | |
| SCHEMBL16752817 | 0.84 | MAP2K4 (0.44) | MAPK1MAP2K4CDK2 | |
| SCHEMBL18557814 | 0.83 | RAB9A (0.48) | POLBALDH1A1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |