Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976833 | 0.93 | HPGD (0.41) | MAPK1DGAT2HPGDLMNAKDM4E | |
| SCHEMBL19976770 | 0.92 | MAPK1 (0.38) | MAPK1DGAT2HPGDNAMPTALDH1A1 | |
| SCHEMBL19976784 | 0.91 | MAPK1 (0.38) | MAPK1DGAT2NAMPTMAP2K4POLB | |
| SCHEMBL19976786 | 0.91 | HPGD (0.48) | MAPK1DGAT2HPGDNAMPTLMNA | |
| SCHEMBL19976928 | 0.89 | CTNNB1 (0.37) | MAPK1HPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL19976807 | 0.86 | MAPK1 (0.37) | MAPK1DGAT2HPGDNAMPTPOLB | |
| SCHEMBL19976806 | 0.85 | HPGD (0.51) | MAPK1HPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL18558194 | 0.83 | RAB9A (0.47) | KDM4EALDH1A1GAA | |
| SCHEMBL18558474 | 0.82 | RAB9A (0.43) | MAPK1HPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL19976777 | 0.82 | POLB (0.39) | MAPK1DGAT2HPGDNAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |