Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 13/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976786 | 0.91 | HPGD (0.48) | MAPK1HPGDPRKD1NAMPTDGAT2 | |
| SCHEMBL19976770 | 0.91 | MAPK1 (0.38) | MAPK1HPGDNAMPTPOLBDGAT2 | |
| SCHEMBL19976784 | 0.88 | MAPK1 (0.38) | MAPK1NAMPTPOLBDGAT2 | |
| SCHEMBL19976803 | 0.86 | MAPK1 (0.38) | MAPK1HPGDNAMPTPOLBDGAT2 | |
| SCHEMBL19976806 | 0.84 | HPGD (0.51) | MAPK1HPGDPRKD1POLB | |
| SCHEMBL19976777 | 0.80 | POLB (0.39) | MAPK1HPGDPRKD1NAMPTPOLB | |
| SCHEMBL19976833 | 0.79 | HPGD (0.41) | MAPK1HPGDPOLBDGAT2 | |
| SCHEMBL19976944 | 0.79 | MAPK1 (0.36) | MAPK1HPGDNAMPTPOLB | |
| SCHEMBL19976798 | 0.77 | PTGES (0.36) | MAPK1POLBDGAT2 | |
| SCHEMBL19976739 | 0.76 | HPGD (0.37) | MAPK1HPGDPRKD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |