Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977036 | 0.89 | JAK2 (0.64) | SMN1; SMN2HTTMEN1KMT2ARXFP1 | |
| SCHEMBL3658406 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AALDH1A1HTTHPGD | |
| Hydrochloric Acid SCHEMBL7268198 | 0.84 | MEN1 (0.47) | SMN1; SMN2RAB9AALDH1A1HTTHPGD | |
| SCHEMBL9222065 | 0.82 | HSD17B10 (0.59) | SMN1; SMN2RAB9AALDH1A1HTTHPGD | |
| SCHEMBL7413732 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AALDH1A1HPGDHDAC8 | |
| SCHEMBL28743340 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AALDH1A1HPGDHDAC8 | |
| SCHEMBL19976922 | 0.81 | HPGD (0.66) | SMN1; SMN2RAB9AALDH1A1HTTHPGD | |
| SCHEMBL11431508 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAGFER | |
| SCHEMBL19977124 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2796740 | 0.80 | CA1 (0.62) | SMN1; SMN2RAB9AALDH1A1HPGDHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |