Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977018 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNARAB9ANPC1KMT2A | |
| SCHEMBL19976922 | 0.84 | HPGD (0.66) | SMN1; SMN2LMNARAB9ANPC1ALDH1A1 | |
| SCHEMBL19976977 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL19977069 | 0.81 | ALDH1A1 (0.57) | SMN1; SMN2LMNARAB9AALDH1A1MAPT | |
| SCHEMBL19976980 | 0.80 | NPC1 (0.66) | LMNARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL19976955 | 0.80 | POLB (0.53) | SMN1; SMN2LMNARAB9ANPC1ALDH1A1 | |
| SCHEMBL19976893 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL19976950 | 0.80 | ALDH1A1 (0.51) | SMN1; SMN2LMNARAB9ANPC1KMT2A | |
| SCHEMBL19976892 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNARAB9ANPC1KMT2A | |
| SCHEMBL19976971 | 0.79 | HDAC1 (0.53) | SMN1; SMN2LMNARAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |