Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | SCN1A | P35498 | 1/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976955 | 0.90 | POLB (0.53) | HPGDPOLBPGRSCN1ASCN2A | |
| SCHEMBL19976974 | 0.88 | MEN1 (0.58) | HPGDPOLBPGRSCN1ASCN2A | |
| SCHEMBL19977019 | 0.85 | ALDH1A1 (0.61) | HPGDPOLBPGRSCN1ASCN2A | |
| SCHEMBL19976994 | 0.85 | PGR (0.57) | HPGDPOLBPGRSCN1ASCN2A | |
| SCHEMBL19976950 | 0.84 | ALDH1A1 (0.51) | HPGDPOLBLMNAGAAMAPT | |
| SCHEMBL19976953 | 0.84 | LMNA (0.56) | POLBLMNAGAAMAPTHTT | |
| SCHEMBL19976951 | 0.84 | HDAC1 (0.51) | HPGDPOLBLMNAMAPTHTT | |
| SCHEMBL19977124 | 0.84 | SMN1; SMN2 (0.62) | LMNAGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19976956 | 0.83 | PGR (0.53) | HPGDPOLBPGRSCN1ASCN2A | |
| SCHEMBL19977069 | 0.82 | ALDH1A1 (0.57) | HPGDPOLBLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |