Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | TYK2 | P29597 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976892 | 0.89 | SMN1; SMN2 (0.56) | HTTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3658406 | 0.79 | SMN1; SMN2 (0.59) | HTTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL164882 | 0.79 | JAK2 (1.00) | JAK2TYK2HTTEPHX1SMN1; SMN2 | |
| SCHEMBL19977038 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2POLBLMNAKDM4EL3MBTL1 | |
| SCHEMBL16999266 | 0.78 | JAK2 (0.57) | JAK2TYK2SMN1; SMN2POLBSTAT3 | |
| SCHEMBL13255721 | 0.76 | LMNA (0.56) | HTTSMN1; SMN2LMNAKDM4EL3MBTL1 | |
| SCHEMBL5131090 | 0.76 | CA2 (0.57) | HTTLMNAKDM4EROCK2ROCK1 | |
| SCHEMBL2917517 | 0.76 | CA2 (0.57) | HTTLMNAKDM4EROCK2ROCK1 | |
| SCHEMBL7413732 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNA | |
| SCHEMBL28743340 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |