Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977139 | 0.91 | KDM4E (0.42) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL19977021 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL16999359 | 0.83 | USP30 (0.48) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL16999788 | 0.83 | USP30 (0.48) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL19977083 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL4451781 | 0.77 | KMT2A (0.52) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL16999843 | 0.77 | USP30 (0.49) | — | |
| SCHEMBL19977082 | 0.76 | KCNQ2 (0.65) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19976934 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL19977048 | 0.75 | KCNQ2 (0.64) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |