Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976981 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2ABCG2ABCB1ALDH1A1LMNA | |
| SCHEMBL19977021 | 0.86 | ALDH1A1 (0.51) | SMN1; SMN2ABCG2ABCB1ALDH1A1KMT2A | |
| SCHEMBL16999791 | 0.82 | USP30 (0.48) | ABCG2ABCB1KMT2A | |
| SCHEMBL19977020 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ABCG2ABCB1ALDH1A1KMT2A | |
| SCHEMBL19977140 | 0.78 | ATM (0.52) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL19977082 | 0.77 | KCNQ2 (0.65) | SMN1; SMN2ALDH1A1LMNAKCNQ2PLA2G1B | |
| SCHEMBL19976934 | 0.77 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1LMNAGFERKCNQ2 | |
| SCHEMBL4468269 | 0.77 | ABCG2 (0.44) | SMN1; SMN2ABCG2ABCB1ALDH1A1KCNQ2 | |
| SCHEMBL19977048 | 0.76 | KCNQ2 (0.64) | SMN1; SMN2ALDH1A1LMNAKCNQ2PLA2G1B | |
| SCHEMBL19977050 | 0.75 | MAPK1 (0.63) | SMN1; SMN2ALDH1A1KCNQ2PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |