Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462502 | 0.77 | POLB (0.42) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL19977020 | 0.77 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL21893901 | 0.77 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL3711804 | 0.77 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15452611 | 0.76 | KMT2A (0.59) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL30982330 | 0.76 | HCRTR1 (0.51) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL4454936 | 0.73 | ABCB1 (0.40) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL4468269 | 0.73 | ABCG2 (0.44) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL13078833 | 0.71 | ALDH1A1 (0.45) | ALDH1A1POLBKDM4ECYP1A2CYP2C9 | |
| SCHEMBL1165268 | 0.71 | SMN1; SMN2 (0.53) | ALDH1A1MAPTPOLBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |