Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.54 |
| ▸ | EIF4H | Q15056 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976939 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KDM4EPABPC1EIF4HMEN1 | |
| SCHEMBL19976933 | 0.87 | PABPC1 (0.73) | ALDH1A1KDM4EPABPC1EIF4HMEN1 | |
| SCHEMBL19976894 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4EPABPC1EIF4HMEN1 | |
| SCHEMBL16999703 | 0.83 | KDM4E (0.53) | ALDH1A1KDM4EPABPC1EIF4HCYP1A2 | |
| SCHEMBL16994059 | 0.83 | KDM4E (0.53) | ALDH1A1KDM4EPABPC1EIF4HCYP1A2 | |
| SCHEMBL19977029 | 0.80 | KDM4E (0.54) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL19977103 | 0.80 | KMT2A (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL19976946 | 0.78 | ALDH1A1 (0.65) | ALDH1A1KDM4EPABPC1EIF4HMEN1 | |
| SCHEMBL19977086 | 0.78 | XIAP (0.41) | ALDH1A1KDM4EPABPC1EIF4HCYP1A2 | |
| SCHEMBL19976906 | 0.78 | PGR (0.52) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |