Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28208633 | 0.80 | POLB (0.65) | SMN1; SMN2POLBRAB9ANPC1PKM | |
| SCHEMBL30887863 | 0.80 | POLB (0.65) | SMN1; SMN2POLBRAB9ANPC1PKM | |
| SCHEMBL13255724 | 0.80 | POLB (0.65) | SMN1; SMN2POLBRAB9ANPC1PKM | |
| SCHEMBL29366822 | 0.80 | RAB9A (0.89) | SMN1; SMN2RAB9ANPC1PKMNPSR1 | |
| SCHEMBL997866 | 0.80 | RAB9A (0.89) | SMN1; SMN2RAB9ANPC1PKMNPSR1 | |
| SCHEMBL19976958 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBRAB9ANPC1NPSR1 | |
| Hydrochloric Acid SCHEMBL30887874 | 0.79 | POLB (0.63) | SMN1; SMN2POLBRAB9ANPC1PKM | |
| SCHEMBL16999083 | 0.79 | KMT2A (0.64) | RAB9ANPC1PKMNPSR1MEN1 | |
| SCHEMBL19976892 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1NPSR1MEN1 | |
| SCHEMBL19977036 | 0.78 | JAK2 (0.64) | SMN1; SMN2POLBMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |