Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977083 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2APKMPOLB | |
| SCHEMBL19977140 | 0.87 | ATM (0.52) | SMN1; SMN2ATMMEN1KMT2APOLB | |
| SCHEMBL19977139 | 0.82 | KDM4E (0.42) | SMN1; SMN2MEN1KMT2APKMPOLB | |
| SCHEMBL19977081 | 0.79 | KCNQ2 (0.54) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL19977021 | 0.78 | ALDH1A1 (0.51) | SMN1; SMN2ATMMEN1KMT2APOLB | |
| SCHEMBL19976955 | 0.78 | POLB (0.53) | SMN1; SMN2POLBALDH1A1LMNAMAPT | |
| SCHEMBL19977018 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL19977072 | 0.76 | LMNA (0.54) | SMN1; SMN2KMT2APOLBLMNAGFER | |
| SCHEMBL19977070 | 0.75 | KCNK3 (0.48) | SMN1; SMN2POLBALDH1A1LMNAGFER | |
| SCHEMBL16999791 | 0.74 | USP30 (0.48) | KMT2AABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |