Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 4/20 | 0.48 |
| ▸ | AHR | P35869 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19506591 | 0.79 | GABRA1 (0.51) | HTR2AHTR2CADRB1HTR1AADRA2A | |
| SCHEMBL22179532 | 0.76 | PCSK9 (0.42) | PCSK9AHRHTR2AHTR2CHTR2B | |
| SCHEMBL20718219 | 0.74 | HTR2A (0.49) | HTR2AHTR2CADRB1HTR1AADRA2A | |
| SCHEMBL22179628 | 0.71 | AHR (0.39) | PCSK9AHRHTR2AHTR2CHTR2B | |
| SCHEMBL20088898 | 0.70 | PCSK9 (0.45) | PCSK9AHRHTR2AHTR2CHTR2B | |
| SCHEMBL27439583 | 0.69 | ALOX5 (0.48) | KDM4EMAPTL3MBTL1 | |
| SCHEMBL25497958 | 0.69 | HSD17B10 (0.51) | KDM4EMAPT | |
| SCHEMBL23317711 | 0.69 | HTR2A (0.60) | AHRHTR2AHTR2CADRB1HTR1A | |
| SCHEMBL827572 | 0.69 | HTR2A (0.74) | AHRHTR2AHTR2CADRB1HTR1A | |
| SCHEMBL26054160 | 0.69 | HTR2A (0.56) | AHRHTR2AHTR2CADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |