Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 6/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718219 | 0.87 | HTR2A (0.49) | GABRA1GABRB2HTR2AHTR2CHTR1A | |
| SCHEMBL22209364 | 0.83 | KDM4E (0.45) | GABRA1GABRB2HTR2AHTR2CHTR1A | |
| SCHEMBL13533551 | 0.83 | HTR2A (0.61) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL3197446 | 0.81 | CHRNB2 (0.59) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL27421180 | 0.81 | HTR2A (0.49) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL3173954 | 0.81 | GPR84 (0.67) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL3182374 | 0.81 | GPR84 (0.67) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL22184229 | 0.80 | POLB (0.46) | GABRA1GABRB2HTR2AHTR2CHTR1A | |
| SCHEMBL19977148 | 0.79 | PCSK9 (0.48) | HTR2AHTR2CHTR1AHTR2BHTR1D | |
| SCHEMBL25769074 | 0.79 | HTR2A (0.65) | HTR2AHTR2CHTR1AHTR2BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018129-A1 | COMPOUNDS AS PU. 1 INHIBITORS | S-Infinity Pharmaceuticals (CN) | 2024-01-18 | — | — | US | disclosed |
| US-11084811-B2 | Compounds for treatment of cancer | Oncternal Therapeutics, Inc. (US) | 2021-08-10 | — | — | US | disclosed |
| US-20170304270-A1 | ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084811-B2 | Compounds for treatment of cancer | KLK3, BRDT, ACP3 | GABRA1 4513/4885GABRB2 3240/4885HTR2A 4734/4885 |
| US-20170304270-A1 | ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF | SLC10A1, FXR1, NR1H4 | GABRA1 164/4885GABRB2 159/4885HTR2A 2478/4885 |
| US-20240018129-A1 | COMPOUNDS AS PU. 1 INHIBITORS | FLI1, MCL1, SP1 | GABRA1 2993/4885GABRB2 2630/4885HTR2A 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.