Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14142668 | 0.97 | ALDH1A1 (0.60) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 | |
| SCHEMBL19977300 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 | |
| SCHEMBL19977293 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 | |
| SCHEMBL19977298 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 | |
| SCHEMBL24518243 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 | |
| SCHEMBL24518410 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 | |
| SCHEMBL1173601 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 | |
| SCHEMBL17417851 | 0.91 | ALDH1A1 (0.53) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 | |
| Biphenyl SCHEMBL3652128 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 | |
| Potassium Ion SCHEMBL134847 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TAAR1CYP1A2MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11193915-B2 | Composite material for the detection of chemical species | INSTITUT NATIONAL D'OPTIQUE (CA) | 2021-12-07 | — | — | US | claimed |
| US-20190017978-A1 | COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES | INSTITUT NATIONAL D'OPTIQUE (CA) | 2019-01-17 | — | — | US | claimed |
| WO-2017088069-A1 | COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES | INSTITUT NATIONAL D'OPTIQUE (CA) | 2017-06-01 | — | — | WO | claimed |
| US-8642350-B2 | Sensor material and uses thereof to simultaneously sense two analytes: oxygen and pH or acidic/basic gaseous ions | UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2014-02-04 | — | — | US | claimed |
| EP-2371925-B1 | A sensor material, and uses thereof to simultaneously sense two analytes | UNIV COLLEGE CORK NAT UNIV IE (IE) | 2012-12-12 | — | — | EP | claimed |
| EP-2371925-A1 | A sensor material, and uses thereof to simultaneously sense two analytes | University College Cork, National University of Ireland, Cork (IE) | 2011-10-05 | — | — | EP | claimed |
| US-20110236986-A1 | SENSOR MATERIAL AND USES THEREOF TO SIMULTANEOUSLY SENSE TWO ANALYTES | UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2011-09-29 | — | — | US | claimed |
| US-20240349724-A1 | ANTIMICROBIAL COMPOSITIONS EFFECTIVE AGAINST BACTERIA AND FUNGUS | TerMir Inc. | 2024-10-24 | — | — | US | disclosed |
| US-12059003-B2 | Antimicrobial compositions effective against bacteria and fungus | TerMir Inc. (US) | 2024-08-13 | — | — | US | disclosed |
| WO-2022040799-A1 | ANTIMICROBIAL COMPOSITION | GP TECH INOVASYON TEKNOLOJI VE ARASTIRMA A.S (TR) | 2022-03-03 | — | — | WO | disclosed |
| US-11193915-B2 | Composite material for the detection of chemical species | INSTITUT NATIONAL D'OPTIQUE (CA) | 2021-12-07 | — | — | US | disclosed |
| US-11029293-B2 | Method and system for the detection of a chemical species in solution | INSTITUT NATIONAL D'OPTIQUE (CA) | 2021-06-08 | — | — | US | disclosed |
| EP-3651748-A1 | ANTIMICROBIAL COMPOSITIONS EFFECTIVE AGAINST BACTERIA AND FUNGUS | Termir, Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20190017978-A1 | COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES | INSTITUT NATIONAL D'OPTIQUE (CA) | 2019-01-17 | — | — | US | disclosed |
| WO-2019014424-A1 | ANTIMICROBIAL COMPOSITIONS EFFECTIVE AGAINST BACTERIA AND FUNGUS | TERMIR, INC. (US) | 2019-01-17 | — | — | WO | disclosed |
| US-20180106772-A1 | METHOD AND SYSTEM FOR THE DETECTION OF A CHEMICAL SPECIES IN SOLUTION | INSTITUT NATIONAL D'OPTIQUE (CA) | 2018-04-19 | — | — | US | disclosed |
| WO-2017088069-A1 | COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES | INSTITUT NATIONAL D'OPTIQUE (CA) | 2017-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12059003-B2 | Antimicrobial compositions effective against bacteria and fungus | XDH, MPO, XPA | ALDH1A1 4405/4885TAAR1 1329/4885CYP1A2 3277/4885 |
| US-20240349724-A1 | ANTIMICROBIAL COMPOSITIONS EFFECTIVE AGAINST BACTERIA AND FUNGUS | XDH, MPO, XPA | ALDH1A1 4405/4885TAAR1 1329/4885CYP1A2 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.