Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977569 | 0.92 | — | — | |
| SCHEMBL19977554 | 0.91 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL19977892 | 0.90 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL19977537 | 0.90 | — | — | |
| SCHEMBL19977557 | 0.88 | — | — | |
| SCHEMBL19977694 | 0.88 | — | — | |
| SCHEMBL23184050 | 0.88 | ALDH1A1 (0.37) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL23184480 | 0.86 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL19977547 | 0.84 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4EMAPTNPSR1 | |
| SCHEMBL19977551 | 0.84 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | LG CHEM, LTD. | 2021-08-03 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | RER1, NR2E3, RIF1 | ALDH1A1 227/4885HPGD 3893/4885KDM4E 2668/4885 |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, ERG | ALDH1A1 83/4885HPGD 3365/4885KDM4E 2931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.