Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20347851 | 0.91 | ADAMTS5 (0.33) | ADAMTS5ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL29892647 | 0.91 | ADAMTS5 (0.33) | ADAMTS5ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL21677744 | 0.91 | PDE6D (0.32) | ADORA2AADORA1 | |
| SCHEMBL20347845 | 0.90 | ADAMTS5 (0.33) | ADAMTS5ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL21702809 | 0.90 | ADAMTS5 (0.33) | ADAMTS5ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL21677857 | 0.88 | ADORA2A (0.32) | ADORA2AADORA1 | |
| SCHEMBL15030761 | 0.87 | MEN1 (0.34) | ADAMTS5ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL22065507 | 0.87 | MEN1 (0.41) | ADORA2AADORA1MEN1KMT2AMAPT | |
| SCHEMBL15030880 | 0.86 | MEN1 (0.35) | ADORA2AADORA1MEN1KMT2AMAPT | |
| SCHEMBL20287428 | 0.85 | ADORA2A (0.34) | ADAMTS5ADORA2AADORA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | LG CHEM, LTD. | 2021-08-03 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | RER1, NR2E3, RIF1 | ADAMTS5 4729/4885ADORA2A 3665/4885ADORA1 2504/4885 |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, ERG | ADAMTS5 4198/4885ADORA2A 3440/4885ADORA1 3848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.