Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974596 | 1.00 | LMNA (0.44) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL19974452 | 0.92 | LMNA (0.47) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL22700215 | 0.91 | ALDH1A1 (0.44) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL19974563 | 0.86 | HINT1 (0.40) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL29148038 | 0.85 | LMNA (0.48) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL30303123 | 0.85 | LMNA (0.48) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL18041225 | 0.85 | LMNA (0.48) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL17467485 | 0.85 | LMNA (0.48) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL22700325 | 0.85 | LMNA (0.42) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL20305220 | 0.85 | LMNA (0.47) | LMNAALDH1A1TP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049534-A1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |