Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 12/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979256 | 0.88 | NT5E (0.39) | PDE2AALDH1A1LMNATP53MAPT | |
| SCHEMBL19975506 | 0.88 | NT5E (0.39) | PDE2AALDH1A1LMNATP53MAPT | |
| SCHEMBL22700396 | 0.87 | PDE2A (0.36) | PDE2AALDH1A1LMNATP53MAPT | |
| SCHEMBL19979067 | 0.87 | LMNA (0.40) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL19979002 | 0.86 | PDE2A (0.33) | PDE2AALDH1A1LMNATP53MAPT | |
| SCHEMBL22700325 | 0.80 | LMNA (0.42) | PDE2AALDH1A1LMNATP53MAPT | |
| SCHEMBL19978901 | 0.80 | LMNA (0.46) | PDE2AALDH1A1LMNATP53MAPT | |
| SCHEMBL19975504 | 0.78 | NT5E (0.39) | PDE2AALDH1A1LMNATP53MAPT | |
| SCHEMBL19979260 | 0.75 | PDE2A (0.49) | PDE2ALMNATP53NT5E | |
| SCHEMBL19974569 | 0.74 | ADORA2A (0.41) | ALDH1A1LMNATP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512860-B1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC (CA) | 2020-11-25 | — | — | EP | disclosed |
| WO-2018049534-A1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |