Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979608 | 0.91 | LPAR3 (0.46) | CYP3A4LPAR3LPAR2LPAR1S1PR2 | |
| SCHEMBL19979609 | 0.87 | CYP3A4 (0.39) | CYP3A4LPAR3LPAR2LPAR1LMNA | |
| SCHEMBL14770373 | 0.86 | LPAR3 (0.47) | CYP3A4LPAR3LPAR2LPAR1LMNA | |
| SCHEMBL19979598 | 0.86 | CYP3A4 (0.44) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL19979590 | 0.86 | CYP3A4 (0.44) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL20049675 | 0.84 | LPAR3 (0.42) | CYP3A4LPAR3LPAR2LPAR1LMNA | |
| SCHEMBL19979597 | 0.84 | CYP3A4 (0.45) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL14778154 | 0.82 | CYP3A4 (0.52) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL14740737 | 0.80 | LPAR3 (0.46) | LPAR3LPAR2LPAR1ESR1TSHR | |
| SCHEMBL16238472 | 0.80 | LPAR3 (0.42) | CYP3A4LPAR3LPAR2LPAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414784-B2 | Aminobisphosphonate antiwear additives | AFTON CHEMICAL CORPORATION (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180099985-A1 | Novel AminoBisPhosphonate Antiwear Additives | AFTON CHEMICAL CORP (US) | 2018-04-12 | — | — | US | disclosed |
| US-20180099985-A1 | Novel AminoBisPhosphonate Antiwear Additives | AFTON CHEMICAL CORP (US) | 2018-04-12 | — | — | US | disclosed |
| WO-2018053407-A1 | NOVEL AMINOBISPHOSPHONATE ANTIWEAR ADDITIVES | AFTON CHEMICAL CORPORATION (US) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099985-A1 | Novel AminoBisPhosphonate Antiwear Additives | SOST, PSPH, FIBP | CYP3A4 4743/4885LPAR3 1425/4885LPAR2 2993/4885 |
| US-10414784-B2 | Aminobisphosphonate antiwear additives | SOST, AASDHPPT, SLC35B2 | CYP3A4 4608/4885LPAR3 1673/4885LPAR2 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.