Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980105 | 0.82 | MAPT (0.44) | SMN1; SMN2HTTHSP90AA1MAPTTSHR | |
| SCHEMBL1578863 | 0.74 | MEN1 (0.45) | MAPTKMT2AALDH1A1RAB9A | |
| SCHEMBL422881 | 0.73 | TSHR (0.52) | MAPTTSHRCASP1CA12CA1 | |
| SCHEMBL609984 | 0.73 | KDM4E (0.54) | MAPTTSHRNPC1CA12CA1 | |
| SCHEMBL29550931 | 0.73 | TSHR (0.52) | MAPTTSHRCASP1CA12CA1 | |
| SCHEMBL6306356 | 0.72 | TSHR (0.50) | HTTMAPTTSHRCASP1NPC1 | |
| SCHEMBL510186 | 0.71 | ALDH1A1 (0.51) | SMN1; SMN2MAPTTSHRNPC1LMNA | |
| SCHEMBL9630374 | 0.71 | TSHR (0.49) | HSP90AA1MAPTTSHRCASP1CA12 | |
| SCHEMBL5734578 | 0.70 | MAPT (0.62) | SMN1; SMN2HTTHSP90AA1MAPTTSHR | |
| SCHEMBL8301932 | 0.70 | MAPT (0.55) | SMN1; SMN2HTTHSP90AA1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |