Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979917 | 0.82 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2HSP90AA1HTTNPC1 | |
| SCHEMBL19979894 | 0.81 | KDM4E (0.40) | MAPTSMN1; SMN2KDM4EHPGDTSHR | |
| SCHEMBL19980188 | 0.79 | KDM4E (0.40) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL1498542 | 0.76 | KDM4E (0.50) | NPC1RAB9AKDM4EHPGDTSHR | |
| SCHEMBL31697314 | 0.76 | KDM4E (0.50) | NPC1RAB9AKDM4EHPGDTSHR | |
| SCHEMBL23169063 | 0.74 | MEN1 (0.49) | MAPTKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL28944494 | 0.74 | KDM4E (0.48) | MAPTSMN1; SMN2HSP90AA1NPC1RAB9A | |
| SCHEMBL29827383 | 0.74 | KDM4E (0.48) | MAPTSMN1; SMN2HSP90AA1NPC1RAB9A | |
| SCHEMBL24834467 | 0.74 | KDM4E (0.48) | MAPTKDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL4192553 | 0.74 | KDM4E (0.58) | MAPTNPC1RAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |