Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979898 | 0.91 | HPGD (0.48) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19980126 | 0.90 | HPGD (0.43) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19980109 | 0.89 | NPC1 (0.40) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19980213 | 0.86 | POLB (0.44) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19980217 | 0.78 | GAA (0.38) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19980104 | 0.73 | KDM4E (0.39) | CYP1A2CYP2C9CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL19979834 | 0.72 | POLB (0.47) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19980130 | 0.72 | POLB (0.41) | LMNAPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL19979837 | 0.71 | POLB (0.52) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19979956 | 0.71 | ALDH1A1 (0.33) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |