Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980213 | 0.78 | POLB (0.44) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL19980217 | 0.78 | GAA (0.38) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL19980109 | 0.76 | NPC1 (0.40) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL19979894 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL19979898 | 0.74 | HPGD (0.48) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL19980105 | 0.73 | MAPT (0.44) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL19979955 | 0.73 | HPGD (0.39) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL19980126 | 0.73 | HPGD (0.43) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL19980223 | 0.71 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL29883555 | 0.69 | XPO1 (0.56) | KDM4ETP53ALOX15ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |